[HTML][HTML] Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor …
Y Kim, K Sato, M Asagiri, I Morita, K Soma… - Journal of Biological …, 2005 - ASBMB
Bone homeostasis depends on the coordination of osteoclastic bone resorption and
osteoblastic bone formation. Receptor activator of NF-κB ligand (RANKL) induces osteoclast
differentiation through activating a transcriptional program mediated by the key transcription
factor nuclear factor of activated T cells (NFAT) c1. Immunoreceptors, including osteoclast-
associated receptor (OSCAR) and triggering receptor expressed by myeloid cells (TREM)-2,
constitute the co-stimulatory signals required for RANKL-mediated activation of calcium …
osteoblastic bone formation. Receptor activator of NF-κB ligand (RANKL) induces osteoclast
differentiation through activating a transcriptional program mediated by the key transcription
factor nuclear factor of activated T cells (NFAT) c1. Immunoreceptors, including osteoclast-
associated receptor (OSCAR) and triggering receptor expressed by myeloid cells (TREM)-2,
constitute the co-stimulatory signals required for RANKL-mediated activation of calcium …