Peripherally applied Aβ-containing inoculates induce cerebral β-amyloidosis
Science, 2010•science.org
The intracerebral injection of β-amyloid–containing brain extracts can induce cerebral β-
amyloidosis and associated pathologies in susceptible hosts. We found that intraperitoneal
inoculation with β-amyloid–rich extracts induced β-amyloidosis in the brains of β-amyloid
precursor protein transgenic mice after prolonged incubation times.
amyloidosis and associated pathologies in susceptible hosts. We found that intraperitoneal
inoculation with β-amyloid–rich extracts induced β-amyloidosis in the brains of β-amyloid
precursor protein transgenic mice after prolonged incubation times.
The intracerebral injection of β-amyloid–containing brain extracts can induce cerebral β-amyloidosis and associated pathologies in susceptible hosts. We found that intraperitoneal inoculation with β-amyloid–rich extracts induced β-amyloidosis in the brains of β-amyloid precursor protein transgenic mice after prolonged incubation times.
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