[HTML][HTML] Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury
CG Lian, EM Bueno, SR Granter, AC Laga… - Modern Pathology, 2014 - Elsevier
This series of 113 sequential biopsies of full facial transplants provides findings of potential
translational significance as well as biological insights that could prompt reexamination of
conventional paradigms of effector pathways in skin allograft rejection. Serial biopsies
before, during, and after rejection episodes were evaluated for clinicopathological
assessment that in selected cases included specific biomarkers for donor-versus-recipient T
cells. Histologic evidence of rejection included lymphocyte-associated injury to epidermal …
translational significance as well as biological insights that could prompt reexamination of
conventional paradigms of effector pathways in skin allograft rejection. Serial biopsies
before, during, and after rejection episodes were evaluated for clinicopathological
assessment that in selected cases included specific biomarkers for donor-versus-recipient T
cells. Histologic evidence of rejection included lymphocyte-associated injury to epidermal …