Chorioamnionitis and early lung inflammation in infants in whom bronchopulmonary dysplasia develops
KL Watterberg, LM Demers, SM Scott, S Murphy - Pediatrics, 1996 - publications.aap.org
Objective. The development of bronchopulmonary dysplasia (BPD) often has been attributed
to injury from mechanical ventilation and supplemental oxygen. Early lung inflammation in
infants with BPD has been thought to be secondary to these factors. The purpose of this
study was to evaluate whether preexisting (prenatal) inflammation may be a primary
causative factor in the development of BPD. Methods. Intubated newborns of less than 2000
g birth weight were prospectively enrolled. The presence or absence of chorioamnionitis …
to injury from mechanical ventilation and supplemental oxygen. Early lung inflammation in
infants with BPD has been thought to be secondary to these factors. The purpose of this
study was to evaluate whether preexisting (prenatal) inflammation may be a primary
causative factor in the development of BPD. Methods. Intubated newborns of less than 2000
g birth weight were prospectively enrolled. The presence or absence of chorioamnionitis …
