Mitochondria are highly dynamic organelles and their proper function is crucial for the
maintenance of cellular homeostasis. Mitochondrial biogenesis and mitophagy are two
pathways that regulate mitochondrial content and metabolism preserving homeostasis. The
tight regulation between these opposing processes is essential for cellular adaptation in
response to cellular metabolic state, stress and other intracellular or environmental signals.
Interestingly, imbalance between mitochondrial proliferation and degradation process …