Aging, inflammation and the environment

A Bektas, SH Schurman, R Sen, L Ferrucci - Experimental gerontology, 2018 - Elsevier
The aging process is driven by interrelated mechanisms that lead to the emergence of
characteristic phenotypes that include changes in body composition, energy production and
utilization imbalance, homeostatic dysregulation, and neurodegeneration and loss of
neuroplasticity. Mainstream theories of aging all recognize that the aging phenotypes result
from an imbalance between stressors and stress buffering mechanisms and a resultant loss
of compensatory reserve leading to accumulation of unrepaired damage. This in turn results …